Alcohol is an organic compound that appears in a variety of forms. The ingestible form, for both legitimate and abuse purposes, is ethanol. It is and has been historically used for hygienic, dietary, medicinal, religious, and recreational purposes.
Barbiturates are central nervous system (CNS) depressants with a wide range of effects and uses: mild sedation to total anesthesia, hypnotics, anticonvulsants (epilepsy), migraine treatment (in fioricet), capital punishment, and assisted suicide where legal.
Because of its low opiate effect, buprenorphine has a lower potential for abuse than other opioid drugs, but it can still be abused through crushing of tablets for snorting or for injection preparations.
GHB is abused as an intoxicant, often in the club, rave and party scene, to produce euphoria and sociability. Small doses can act as a stimulant and aphrodisiac. It is also notorious for use as a date rape drug, although studies have indicated that it is not used as frequently for that purpose as other drugs, such as cocaine.
Ketamine is an anesthetic drug used in human and veterinary medicine, primarily for general anesthesia, although it is sometimes used as a sedative for seriously injured patients and as a painkiller in cases of extreme pain.
Marijuana is a preparation of the cannabis plant for use as a psychoactive drug and as medicine. The principal psychoactive constituent of marijuana is tetrahydrocannabinol (THC), one of hundreds of compounds in the plant.
Methadone is a synthetic opioid used for pain and to treat addiction in patients with opioid dependence. It is chemically closely related to heroin and morphine and has many of the same effects, yet, if used correctly, it is medically safe.
Methamphetamine is psychostimulant in the amphetamine class. It has medical uses in the treatment of attention deficit hyperactivity disorder (ADHD) and obesity. It has a high potential for abuse and medical use comes with tightly controlled regulatory restrictions.
MDMA is synthesized drug in the amphetamine class. It is classed as an empathogenic drug, meaning it produces emotional and social effects that tend to increase a sense of intimacy and diminished anxiety with others, while possibly inducing euphoria and mild hallucinogenic effects.