Marijuana is a preparation of the cannabis plant for use as a psychoactive drug and as medicine. The principal psychoactive constituent of marijuana is tetrahydrocannabinol (THC), one of hundreds of compounds in the plant.

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Methadone is a synthetic opioid used for pain and to treat addiction in patients with opioid dependence. It is chemically closely related to heroin and morphine and has many of the same effects, yet, if used correctly, it is medically safe.

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Methamphetamine is psychostimulant in the amphetamine class. It has medical uses in the treatment of attention deficit hyperactivity disorder (ADHD) and obesity. It has a high potential for abuse and medical use comes with tightly controlled regulatory restrictions.

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While opiate and opioid are often used interchangeably, true opiates are a group of opioid drugs found only in the poppy plant: morphine (and its derivative, heroin), codeine and thebaine.

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Tramadol is an synthetic opioid analgesic with some antidepressant effects. It is used to treat moderate to moderate-severe pain. It is used and metabolized in the body similarly to codeine.

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